Skin Disorders
The biggest organ of the body, the skin, is responsible for safeguarding the body from injury from the outside world. It controls body temperature, keeps the body hydrated, and gives the brain sensory input.
Skin health is crucial because it shields the body from external aggressors like the sun's UV radiation, which may age the skin and raise the risk of skin cancer.
Apart from environmental causes, keeping excellent skin health is crucial since it may lead to a variety of skin illnesses, some of which are potentially fatal.
Skin health is influenced by many variables, such as a healthy diet, enough hydration, sun protection, and abstaining from dangerous chemicals like cigarette smoke and excessive alcohol intake [1].
Regular washing with soap and water and other good hygiene practices can support the maintenance of healthy skin.
A dermatologist's regular skin checkups and the use of high-quality skincare products can both aid in the early detection of skin issues and diseases.
Acne vulgaris, one of the most prevalent skin conditions, affects 80% of people throughout their adolescent years.
The overproduction of sebum by sebaceous glands, which causes blocked hair follicles, irritation, and the development of tiny to big pimples, is the cause of acne.
Although acne is not a skin condition that might endanger life, it can nonetheless be extremely upsetting emotionally and harm confidence and self-esteem.
Triggers including allergies, stress, and dry weather conditions are among the environmental and genetic elements that contribute to its development. [2]
Avoiding irritants, moisturizing the skin with cream and ointments, and staying away from things that set off flare-ups are the usual steps in managing eczema.
Skin cancer is the most prevalent cancer worldwide, with more than 3 million non-melanoma cases identified each year. Anyone can develop skin cancer, regardless of age or skin type.
If untreated, melanoma, the most aggressive variety of skin cancer, can be fatal.
Skin cancer risk can be decreased by taking preventative steps, such as avoiding excessive sun exposure, covering up with protective clothing, using chemical or physical sunscreens, and having frequent dermatologist skin inspections.
How to Prevent Skin Disorders
Keeping your skin in great shape is essential to your entire health and well-being, to sum up. Skin conditions including acne, eczema, and skin cancer can be extremely harmful, but these risks can be reduced with early identification and treatment.
Consistent self-care routines can lead to healthier skin, including maintaining good hygiene habits, utilizing high-quality skincare products, and scheduling routine dermatologist visits [3].
To lower the risk of skin problems and diseases, it is crucial to be initiative-taking about skin health by adopting preventative measures, such as avoiding excessive sun exposure.
Several herbal treatments are also available for sin impairments. An important compound that has a crucial role in improving skin health is EGCG. The mechanisms of action of this compound in improving skin health will be discussed in this article.
EGCG (Epigallocatechin gallate)
It is an important compound obtained from a unique plant. It has been found that many health benefits can be obtained from this precious compound.
It can help in many bad health conditions including inflammation, cancer, and heart and brain disorders. This compound is also helpful in weight loss.
It is normally called catechin. Catechins are very important antioxidant compounds. So, it can protect the cells from oxidative damage that may be caused by free radicals in the cells [4].
EGCG is found in many of the foods that are in our daily use. Some of these foods containing EGCG include:
Some fruits include strawberries, blackberries, pears, cherries, peaches, apples, and avocados.
Tea (black, green, and white)
Nuts including pistachios and pecans.
It is also found in dark chocolate, red wine, and legumes.
EGCG is a well-researched catechin with a lot of health benefits for humans.
Research has also proven it to be very beneficial for maintaining normal body weight and helping in reducing weight in many disorders. Many experiments have been performed for this purpose that will be discussed later in this article.
Many bad health conditions can be treated using this precious compound [5].
The most common health benefits that can be obtained from this compound include:
Help with cardiovascular disorders.
Neuroprotective properties.
It is an anti-allergy compound.
It has anti-microbial properties.
Improves the cognitive functions of the body.
It helps in weight loss.
Promotes osteogenesis.
Boosts the metabolism of the body.
It is an anti-aging compound.
Killing of malignant cells.
It boosts the immune system of the body.
Reduces oxidative stress.
Reduces inflammation.
It maintains healthy skin.
EGCG is an important compound that helps in the treatment of many disorders and works via different mechanisms of action in the body [6].
The most common ways by which EGCG can help the body improve its health conditions are as follows:
The process of oxidation is crucial to maintaining the body's health. We categorize EGCG as an antioxidant based on the chemical structure of the compound. The ring structure in the ECGC traps the free electrons and prevents the formation of reactive oxygen species. It also possesses anti-inflammatory action by targeting the NF-KB pathway and increasing the anti-inflammatory substance’s gene expression.
Moreover, EGCG has demonstrated therapeutic and preventative effects in a variety of human malignancies. Several theories have been put out to explain how EGCG inhibits the development and spread of cancer.
One of the most prevalent and dangerous illnesses affecting humans is cancer. Both the scientific community and the general public have paid close attention to EGCG as a natural substance.
Several skincare treatments for anti-aging contain green tea extract or EGCG. This is so that the chemical can promote young and healthy-looking skin by increasing skin elasticity. Minimizing wrinkles, enhancing moisture retention, and improving skin texture, also slows down the aging process of the skin.
The prooxidant effects of EGCG were considered to represent possible anticancer action mechanisms. Depending on the cell type, dosage, and/or timing of the therapy, several anticancer strategies were used [7].
Several research studies have looked at the mechanisms behind the anti-obesity benefits of EGCG in both cellular and animal models. It can reduce weight through its fat-burning property.
EGCG and Skin Health
A lot of research has been done on EGCG compounds to study their roles in improving the health of the skin and preventing and treating many skin impairments. It has been found that EGCG has several characteristics that can make it suitable for this action and it can act through multiple processes on the skin using these properties.
EGCG has an important role in reducing the inflammation in the skin and in this way, it can improve skin health as well as it can help in treating many skin impairments resulting from inflammation.
EGCG also has a crucial role in reducing the aging effects on the skin. It can help in removing wrinkles from the skin and make it look healthier and young.
This crucial compound also plays role in decreasing the oxidative stress in the dermal cells. It can protect the skin cells from damage and also helps in the repair of these cells if they get damaged by some external factors. In this way, it can help in curing many skin impairments [8].
EGCG is also known for its anti-microbial actions. It can kill all the pathogens which can cause skin infections. By killing such microbes, EGCG can help in curing skin infections as well as preventing many skin illnesses caused by these pathogens.
It has also been found that EGCG can increase the synthesis of collagen in the skin. Doing so can also help in healing skin wounds and improving skin health [9].
EGCG can act by any of these processes and can be a promising compound in improving skin health as well as a therapy for many skin illnesses.
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